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1.
Respiratory benefit in preterm lambs is progressively lost when the concentration of fetal plasma betamethasone is titrated below two nanograms per milliliter.
Am J Physiol Lung Cell Mol Physiol
; 325(5): L628-L637, 2023 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37697929
2.
One percent of the clinical dose used for antenatal steroid therapy is sufficient to induce lung maturation when administered directly to the preterm ovine fetus.
Am J Physiol Lung Cell Mol Physiol
; 322(6): L853-L865, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35438005
3.
Continuous but not pulsed low-dose fetal betamethasone exposures extend the durability of antenatal steroid therapy.
Am J Physiol Lung Cell Mol Physiol
; 322(6): L784-L793, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35380907
4.
Low-dose antenatal betamethasone treatment achieves preterm lung maturation equivalent to that of the World Health Organization dexamethasone regimen but with reduced endocrine disruption in a sheep model of pregnancy.
Am J Obstet Gynecol
; 227(6): 903.e1-903.e16, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35792176
5.
Pharmacokinetics of levonorgestrel and etonogestrel in rat or minipig following intravenous, subcutaneous, or intradermal administration.
Xenobiotica
; 52(6): 575-582, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35975955
6.
Antenatal corticosteroids: a reappraisal of the drug formulation and dose.
Pediatr Res
; 89(2): 318-325, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33177675
7.
Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women.
J Pharmacokinet Pharmacodyn
; 48(3): 411-438, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33954911
8.
Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women.
J Pharmacokinet Pharmacodyn
; 48(2): 261-272, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33389521
9.
Efficacy and safety of ETC-1002, a novel investigational low-density lipoprotein-cholesterol-lowering therapy for the treatment of patients with hypercholesterolemia and type 2 diabetes mellitus.
Arterioscler Thromb Vasc Biol
; 34(3): 676-83, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24385236
10.
Minimal physiologically-based hybrid model of pharmacokinetics in pregnant women: Application to antenatal corticosteroids.
CPT Pharmacometrics Syst Pharmacol
; 12(5): 668-680, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36917704
11.
Antenatal corticosteroids in Singapore: A clinical and scientific assessment.
Singapore Med J
; 2022 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36254928
12.
Application of exposure bracketing to streamline the development of contraceptive products.
Contracept X
; 4: 100072, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35243326
13.
Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.
Bioorg Med Chem Lett
; 21(9): 2725-31, 2011 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21183342
14.
Estimating fetal exposure to the P-gp substrates, corticosteroids, by PBPK modeling to inform prevention of neonatal respiratory distress syndrome.
CPT Pharmacometrics Syst Pharmacol
; 10(9): 1057-1070, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34273255
15.
Tenofovir Alafenamide for HIV Prevention: Review of the Proceedings from the Gates Foundation Long-Acting TAF Product Development Meeting.
AIDS Res Hum Retroviruses
; 37(6): 409-420, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33913760
16.
Pharmacokinetics and Pharmacodynamics of Intramuscular and Oral Betamethasone and Dexamethasone in Reproductive Age Women in India.
Clin Transl Sci
; 13(2): 391-399, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31808984
17.
Evaluation of Maternal Drug Exposure Following the Administration of Antenatal Corticosteroids During Late Pregnancy Using Physiologically-Based Pharmacokinetic Modeling.
Clin Pharmacol Ther
; 106(1): 164-173, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30924921
18.
Oral dosing for antenatal corticosteroids in the Rhesus macaque.
PLoS One
; 14(9): e0222817, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31536601
19.
Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib.
Arthritis Rheumatol
; 67(3): 616-25, 2015 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25470338
20.
The Pharmacokinetics and Pharmacodynamics of Methylprednisolone in Chronic Renal Failure.
Am J Ther
; 1(1): 49-57, 1994 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-11835067